Professor Liang Cheng and colleagues published a new article “Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production” in Cell Death and Disease.  Mesenchymal stem cells (MSCs) and tumor microenvironment (TME) play a pivotal role in driving tumor progression and modulating therapeutic responses. In this investigation, they  demonstrated that MSCs can enhance mitochondrial autophagy and biogenesis of bladder cancer cells, and increase energy production, thereby promoting urothelial cancer progression. Based on their findings, the authors also proposed a novel therapeutic strategy to reverse the pro-tumor effect of MSCs.

Full article is available at the following link: https://rdcu.be/dUB9q